The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.
DJ-1 is a protein with wide subcellular distribution and pleiotropic functions. The loss-of-function mutations of DJ-1 are associated with autosomal recessive early-onset Parkinson's disease yet the ...
A new review in Cold Spring Harbor Perspectives in Biology from the Lippincott-Schwartz Lab at HHMI's Janelia Research Campus examines the diverse endoplasmic reticulum structures that have been ...
New research led by Prof Edward Avezov (UK DRI at Cambridge) reveals how the architecture of the cell’s transport network, the endoplasmic reticulum, can go awry and lead to problems with signalling ...
Inside cells, there exists an extensive system of canals known as the endoplasmic reticulum (ER), which consists of membrane-encased tubes that are partially broken down as needed -- for instance in ...
The endoplasmic reticulum is usually the biggest organelle in eukaryotic cells; it has various portions that serve different purposes; and it is the site of protein production, as well other other ...
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